• Remote haemodynamic monitoring of heart failure

    Updated: 2011-02-28 22:00:11
    Despite improvements in therapy, hospitalisations for heart failure have risen over the past three decades.  More recently, implantable systems for monitoring of intracardiac and pulmonary artery pressures have been developed. In the CHAMPION (CardioMEMS Heart Sensor Allows Monitoring of Pressure to Improve Outcomes in NYHA Class III Heart Failure Patients) trial, patients were implanted with a [...]

  • Ancient History and an Answer We Never Had: Part II

    Updated: 2011-02-24 22:03:09
    Ancient history and an answer we never had… …until now. The common assumption is that if obesity has an increase in cardiovascular events — and death from them — then it is because of a toxic brew of hypertension, increased lipids and diabetes.  Well, you know what assume really stands for?  Assume stands for the contraction makes [...]

  • High Blood Pressure, Cholesterol May Harm Memory

    Updated: 2011-02-24 20:29:02
    French researchers say high blood pressure and high cholesterol are associated with losses in mental abilities and memories in middle age.

  • Brain Stimulation May Ease Treatment-Resistant Hypertension

    Updated: 2011-02-24 20:13:00
    Doctors using deep brain stimulation to treat a hypertensive man's stroke-related pain found that the treatment also consistently lowered the man's blood pressure.

  • Ancient History and an Answer We Never Had: Part I

    Updated: 2011-02-22 21:13:37
    I have been blogging about obesity and its effects on the population as a whole.  For all the discussion about what being obese does, no one has ever figured out the answer to the main question which is, and always will be, “Does It Kill You?”  We know that obesity seems to increase the risk [...]

  • We Will Crush the Earth!

    Updated: 2011-02-17 21:41:06
    Three papers published in The Lancet (Lancet 2011; DOI: 10.1016) highlight the fact that we in the United States know all to well.  It turns out that the whole world is getting fatter except for one very surprising group. Table 1: The International Classification of adult underweight, overweight and obesity according to BMI A graph of [...]

  • The Good, the Bad, and Why It Doesn’t Seem to Matter What they Pay Us (Part 2)

    Updated: 2011-02-15 20:20:33
    In my last blog I outlined how poorly we as physicians treat certain conditions that are defined and that we have relatively good medications for.  One concept that has been floated is the proposal to “pay for performance.”  Now I for one take great exception to the whole principle.  The concept that I wouldn’t do [...]

  • HDL function and atherosclerosis

    Updated: 2011-02-13 16:37:27
    There is a strong inverse relationship between serum levels of HDL and the risk of developing atherosclerotic cardiovascular disease.  This has fostered the search for pharmacological agents that raise HDL, but while several therapies have shown biochemical benefit – including nicotinic acid, fibrates and CETP inhibitors – there are little convincing data to associate these [...]

  • The Good, the Bad, and Why It Doesn’t Seem to Matter What They Pay Us (Part 1)

    Updated: 2011-02-10 20:35:28
    The keeper of much of the information regarding the health, or the lack of it, in the United States is the CDC (Centers for Disease Control).  Using the NHANES or the National Health and Nutrition Examination Survey an attempt is made to obtain a “snapshot” of how we, as a people, are doing health-wise and [...]

  • Your Health Portfolio Part One: Learn How to Manage Your Hypertension

    Updated: 2011-02-09 22:24:09
    In the age of increasing complexity in medical care, it is in a patient’s best interest to take a more active role in health maintenance. It is an irony that many patients have a better handle upon their finances than their own health status. Technological advances allow people to track their financial data, anticipate and [...]

  • New genetic loci for MI and atherosclerosis found

    Updated: 2011-02-08 22:40:24
    Recent genome-wide association studies (GWAS) have identified several novel loci associated with coronary artery disease and myocardial infarction, however these represent only a small proportion of the inherited component of these disorders.  Furthermore, it is not clear whether these loci contribute to the development of atherosclerosis, or whether they may influence the stability of atherosclerotic [...]

  • 911 411 Pradaxa

    Updated: 2011-02-08 20:06:16
    A small piece of vital information has turned up.  Although this is supposed to be “widely” reported, I found out by accident, and I wish to share it with my readers. It seems that Pradaxa that is given to a patient as a 30 day supply comes in a bottle, and the pills are only stable [...]

  • Women Listen Up: Time is Muscle!

    Updated: 2011-02-08 00:37:50
    I hope I caught your attention with this title; if I did, good, read on. I want you to take just a minute to think about your friends and family and the people you care for. I bet a lot of them are women, right? I can honestly say that most of us think that [...]

  • Fewer strokes complicate CABG

    Updated: 2011-02-06 17:39:14
    Stroke is a serious complication of coronary artery bypass grafting (CABG), occurring in around 1.3% of patients undergoing coronary surgery in the USA.  In this study, Tarakji et al. aimed to examine the prevalence and timing of perioperative stroke in the modern era, to identify patient and surgical factors associated with stroke and its timing, [...]

  • PROSPECTing for the answer to what causes myocardial infarctions (Part 2)

    Updated: 2011-02-03 22:35:57
    This study was performed in a group of patients who presented for cardiac catheterization because of an ischemic syndrome — either myocardial infarction or unstable angina. They were not randomized but were asked before there procedure whether they would agree to the evaluation of all of their arteries in several different ways. Those that agreed [...]

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